{"id":56244,"date":"2020-05-08T09:47:26","date_gmt":"2020-05-08T14:47:26","guid":{"rendered":"https:\/\/www.motivationminceur.ca\/?p=56244"},"modified":"2024-01-10T15:04:44","modified_gmt":"2024-01-10T19:04:44","slug":"neurocognitive-and-hormonal-correlates-of-voluntary-weight-loss-in-humans-2","status":"publish","type":"post","link":"https:\/\/www.motivationminceur.ca\/en\/neurocognitive-and-hormonal-correlates-of-voluntary-weight-loss-in-humans-2\/","title":{"rendered":"Neurocognitive and Hormonal Correlates of Voluntary Weight Loss in Humans"},"content":{"rendered":"<div class=\"column\">\n<h1>Neurocognitive and Hormonal Correlates of Voluntary Weight Loss in Humans<\/h1>\n<p>Insufficient responses to hypocaloric diets have been attributed to hormonal adaptations that override self- control of food intake. We tested this hypothesis by measuring circulating energy-balance hormones and brain functional magnetic resonance imaging reactivity to food cues in 24 overweight\/obese participants before, and 1 and 3 months after starting a calorie restriction diet. Increased activity and functional connectivity in prefrontal regions at month 1 correlated with weight loss at months 1 and 3. Weight loss was also correlated with increased plasma ghrelin and decreased leptin, and these changes were associated with food cue reactivity in reward-related brain regions. However, the reduction in leptin did not counteract weight loss; indeed, it was correlated with further weight loss at month 3. Activation in prefrontal regions associated with self-control could contribute to successful weight loss and maintenance. This work supports the role of higher-level cognitive brain function in body-weight regulation in humans.<\/p>\n<\/div>\n<h2>Contacter nous pour plus de d\u00e9tails: <a href=\"mailto:info@motivationminceur.ca\">info@motivationminceur.ca<\/a><\/h2>\n","protected":false},"excerpt":{"rendered":"<p>Neurocognitive and Hormonal Correlates of Voluntary Weight Loss in Humans Insufficient responses to hypocaloric diets have been attributed to hormonal adaptations that override self- control of food intake. We tested this hypothesis by measuring circulating energy-balance hormones and brain functional magnetic resonance imaging reactivity to food cues in 24 overweight\/obese<span class=\"excerpt-hellip\"> [\u2026]<\/span><\/p>\n","protected":false},"author":683,"featured_media":47673,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_uf_show_specific_survey":0,"_uf_disable_surveys":false,"footnotes":""},"categories":[126],"tags":[],"class_list":["post-56244","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-blog"],"_links":{"self":[{"href":"https:\/\/www.motivationminceur.ca\/en\/wp-json\/wp\/v2\/posts\/56244","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.motivationminceur.ca\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.motivationminceur.ca\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.motivationminceur.ca\/en\/wp-json\/wp\/v2\/users\/683"}],"replies":[{"embeddable":true,"href":"https:\/\/www.motivationminceur.ca\/en\/wp-json\/wp\/v2\/comments?post=56244"}],"version-history":[{"count":3,"href":"https:\/\/www.motivationminceur.ca\/en\/wp-json\/wp\/v2\/posts\/56244\/revisions"}],"predecessor-version":[{"id":96397,"href":"https:\/\/www.motivationminceur.ca\/en\/wp-json\/wp\/v2\/posts\/56244\/revisions\/96397"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.motivationminceur.ca\/en\/wp-json\/wp\/v2\/media\/47673"}],"wp:attachment":[{"href":"https:\/\/www.motivationminceur.ca\/en\/wp-json\/wp\/v2\/media?parent=56244"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.motivationminceur.ca\/en\/wp-json\/wp\/v2\/categories?post=56244"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.motivationminceur.ca\/en\/wp-json\/wp\/v2\/tags?post=56244"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}